Fused heteroalkylene quinolinamines, a process and...

Details Fused heteroalkylene quinolinamines, a process and... Fused heteroalkylene quinolinamines, a process and...

C - Chemistry, Metallurgy

07

D

167/208, 260/327

C07D 471/04 (2006.01) C07D 491/04 (2006.01) C07D 491/052 (2006.01) C07D 495/04 (2006.01)

Patent

CA 1322368

ABSTRACT There are disclosed compounds having the formula Image wherein n is 1-4; R is hydrogen, loweralkyl or loweralkylcarbonyl; R1 is hydrogen, loweralkyl, loweralkylcarbonyl, aryl, diloweralkylaminoloweralkyl, arylloweralkyl, diarylloweralkyl, oxygen-bridged arylloweralkyl, or oxygen-bridged diaryllowerallyl; A is a direct bond or (CHR3)m, m being 1-3; X is hydrogen, loweralkyl, cycloalkyl, loweralkoxy, halogen, hydroxy, nitro, trifluoromethyl, formyl, loweralkylcarbonyl, arylcarbonyl, -SH, loweralkylthio, -NHCOR4 or -NR5R6, R4 being hydrogen or loweralkyl, and R5 and R6 being independently hydrogen, loweralkyl or cycloalkyl; Y is O, S or NR7; and each R2, each R3 and R7 are independently hydrogen or loweralkyl, or taken two at a time form a methylene or ethylene group constituting a part of a ring of at least five atoms; stereo, optical and geometrical isomers thereof, and pharmaceutically acceptable acid addition salts thereof, which are useful for enhancing memory.

564915

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