C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/356.2
C07D 311/16 (2006.01) C07D 311/78 (2006.01) C07D 311/80 (2006.01)
Patent
CA 1214781
- 25 - Abstract of the Disclosure: Sulfonates of hydroxycoumarins of the formula I Image (I) where R1 and R2 are identical or different and are each hydrogen, halogen or alkyl of 1 to 5 carbon atoms which can be substituted by -NR4R5, -OR4 or -OC(O)R4, where R4 and R5 are identical or different and are each hydrogen or alkyl of 1 to 4 carbon atoms, or R1 and R2 are each a carboxylic acid group -OC(O)R4 or a car- boxamido radical, with the proviso that R1 is not methyl when R2 is hydrogen, or R1 and R2 together form a -(CH2)n- chain where n is 3 - 5, and R3 is a straight- chain or branched alkyl radical of 1 to 8 carbon atoms or cycloalkyl of 3 to 8 carbon atoms, each of wh;ch can be substituted by halogen, -OR4, -NR4R5, -CN or phenyl, or R3 is a straight-chain or branched alkenyl radical of 3 to 8 carbon atoms, an amino group -NR4R5, or phenyl or naphthyl, each of which is unsubstituted or monosubsti- tuted or polysubstituted by -OR4, -NR4R5, -NO2, halogen, -SR4, -S(O)R4, -OS(O)R4, -SCF3, -OS(O)CF3, -CN, -C(O)R4, -OC(O)R4, -NHC(O)R4, -CF3, C1-C4-alkyl or a combination of these sub- stituents, a process for their preparation, drugs contain- ing these compounds, and compounds of the farmula I, in which R1 is methyl and R2 is hydrogen, for use as drugs.
441580
Hofmann Hans P.
Kreiskott Horst
Lenke Dieter
Mueller Claus D.
Schlecker Rainer
Basf Aktiengesellschaft
Robic Robic & Associes/associates
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