C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/335.5, 260/3
C07D 205/08 (2006.01) C07D 207/28 (2006.01) C07D 405/04 (2006.01) C07D 411/04 (2006.01)
Patent
CA 1199644
ABSTRACT OF THE DISCLOSURE Heterocyclic acetic acid derivatives of the general formula (I), Image (I) wherein y1 and Y2 form together a removable carbonyl protecting group, and X is a selectively removable esterifying group, are prepared by esterifying a compound of the general formula (III), Image (III) wherein y1 and y2 are as defined above and R9 is a removable amido protecting group other than phenyl group, and removing then protecting group R9 of the resulting compound of the general formula (II) Image (II) wherein X, R9, y1 and y2 are as defined above. T he compounds of the general formula (I) are valu- able intermediates of the synthesis of thienamycin and thienamycin analogues.
418741
Doleschall Gabor
Fekete Gyorgy
Fetter Jozsef
Gizur Tibor
Hajos Gyorgy
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Richter Gedeon Vegyesgeti Gyar R.t.
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