Manipulation of ovulation and spawning in fish

A - Human Necessities – 61 – K

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167/103.44

A61K 38/09 (2006.01) A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61K 47/00 (2006.01)

Patent

CA 1338466

Administration into fish of gonadotropin releasing hormone (GnRH), luteinising releasing hormone (LHRH) and their analogs in a polymer based sustained release delivery system was found to induce a prolonged elevation in the fish's plasma level of gonadotropin (GtH), which leads to ovulation and spawning. Such induction of ovulation and spawning was found to occur both within the natural spawning season and outside this season. Such administration thus enables for the first time an effective means for manipulating reproduction in fish, which is a very important factor in the economic management of fish farming.

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