Production of sodium amoxicillin

Details Production of sodium amoxicillin Production of sodium amoxicillin

C - Chemistry, Metallurgy

07

D

260/119.5

C07D 499/68 (2006.01) C07D 499/00 (2006.01)

Patent

CA 1182108

ABSTRACT OF THE DISCLOSURE This specification discloses a process for the production of solid sodium amoxicillin characterized by spray-drying a solution of sodium amoxicillin in aqueous t-butanol. In a preferred embodiment the inlet temperature is about 180°C. and the outlet temperature is about 120°C. Also, the solution to be spray-dried may contain about 1.5 1. t-butanol for each 3.6 1. water.

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