Characterization and detection of sequences associated with...

C - Chemistry – Metallurgy – 12 – Q

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530/7.06, 195/1.

C12Q 1/68 (2006.01) C07H 21/04 (2006.01) C07K 7/06 (2006.01)

Patent

CA 1335967

Four DNA sequences and four corresponding amino acid sequences from the HLA class II DR-beta region of the human genome that are associated with insulin-dependent diabetes mellitus (IDDM) have been identified. These sequences may be used to generate DNA hybridization probes and antibodies for assays in detecting a person's susceptibility for IDDM.

542075

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