Monoclonal antibodies effective in promoting growth

Details Monoclonal antibodies effective in promoting growth Monoclonal antibodies effective in promoting growth

G - Physics

01

N

167/139, 167/37

G01N 33/567 (2006.01) A61K 39/395 (2006.01) G01N 33/577 (2006.01) G01N 33/68 (2006.01) G01N 33/74 (2006.01)

Patent

CA 1295938

-18- MONOCLONAL ANTIBODIES EFFECTIVE IN PROMOTING GROWTH Abstract A correlation has been demonstrated between the ability of an antibody to block the inhibitory action of somatostatin on the gastric inhibitory peptide(GIP)- stimulated release of insulin from the pancreas in vitro and the ability to stimulate growth in vivo. Antibodies. which are identified in the GIP-stimulated insulin release assay are also capable of elevating the levels of growth hormone in vivo.

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