C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
150/3.1
C12Q 1/28 (2006.01) G01N 33/52 (2006.01)
Patent
CA 1225315
ABSTRACT OF THE DISCLOSURE A test composition, device and method for deter- mining a peroxidatively active substance in a test sample, as well as a method for preparing and using the device, are disclosed. The composition comprises an organic hydroperoxide, an indicator capable of providing a detectable response in the presence of the organic hydroperoxide and a peroxidatively active substance, and, as a stabilizing agent, an aniline having the formula: Image in which R1 and R2, same or different, are hydrogen, lower alkyl of from 1 to 6 carbon atoms, phenyl, .alpha.-naphthyl or .beta.-naphthyl; and in which either X1 or X2 is hydrogen, NH2, NO2 or NO, the other of X1 or X2 being hydrogen. The device comprises a carrier matrix incorporated with the composition, and the method for using the device comprises contacting a test sample with the device and observing a detect- able response therein. A method for preparing the device comprises preparing two or more solutions of the ingredients of the composition, wetting the carrier matrix sequentially therewith and drying the matrix after each wetting.
452216
Miles Laboratories Inc.
Osler Hoskin & Harcourt Llp
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