Spiro-quaternary ammonium halides and n-(2- pyrimidinyl)...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/14 (2006.01)

Patent

CA 1175833

MJ 517 SPIRO-QUATERNARY AMMONIUM HALIDES AND N-(2-PYRIMIDINYL)PIPERAZINYLALKYLAZASPIROALKANEDIONE PROCESS Abstract of the Invention Novel spiro-quaternary ammonium halides are disclosed. The new compounds are particularly valuable as intermediates in prepara- tion of N-(2-pyrimidinyl)piperazinylalkyl derivatives of azaspiro- alkanediones such as the psychopharmacologic agent 8-[4-[4-(2-pyrimidinyl)- 1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione.

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