Process for the preparation of 5,6,7 8- tetrahydrofolic acid

Details Process for the preparation of 5,6,7 8- tetrahydrofolic acid Process for the preparation of 5,6,7 8- tetrahydrofolic acid

C - Chemistry, Metallurgy

07

D

260/242.13

C07D 475/04 (2006.01)

Patent

CA 1234570

Abstract A process for the preparation of 5,6,7,8- tetrahydrofolic acid which comprises dissolving and/or suspending folic acid or dihydrofolic acid in an aqueous solution containing an inorganic base, and bringing the resulting solution or suspension into contact with hydrogen in the presence of a noble metal catalyst while maintaining its pH at 5-9, thereby catalytically hydrogenating the folic acid or dihydrofolic acid into 4,5,6,7-tetrahydrofolic acid.

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