Phenoxyamino acid esters and peptide esters

Details Phenoxyamino acid esters and peptide esters Phenoxyamino acid esters and peptide esters

C - Chemistry, Metallurgy

07

K

530/7.04, 260/47

C07K 5/04 (2006.01) C07C 143/75 (1985.01)

Patent

CA 1248697

ABSTRACT New esters, which are substrates for esterolytic and/or proteolytic enzymes are provided which can be used in conjunction with a diazonium salt as the detection principle in an agent for the detection of esterolytic or proteolytic enzymes, the esters are compounds of formula:- Image n which R"1, R"2, R"3 and R"4, which may be the same or different, are hydrogen atoms or lower alkyl, lower alkoxy, alkylamino or dialkylamino radicals or in which two adjacent substituents can also represent a fused benzene ring, A is a residue of an amino acid or of a peptide and B is a nitrogen protective group conventional in peptide chemistry or derived thereform.

456850

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