Pentacyclic triterpenoid compounds as topoisomerase...

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A61K 31/56 (2006.01) A61K 31/165 (2006.01) A61K 31/18 (2006.01) A61K 31/19 (2006.01) A61K 31/195 (2006.01) A61K 31/21 (2006.01) A61K 31/215 (2006.01) A61K 31/70 (2006.01) C07C 62/06 (2006.01) C07C 69/00 (2006.01) C07H 15/256 (2006.01)

Patent

CA 1330944

ABSTRACT OF THE DISCLOSURE Pentacyclic triterpenoid compounds such as .alpha.-boswellic acid and its acetate, .beta.-boswellic acid and its acetate, which have an inhibitory effect on topoisomerase I and topoisomerase II, are disclosed. Compositions based on the pentacyclic triterpenoid compounds which can be used to treat various cancers in mammals are also disclosed.

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