Anti-emetic nortropyl(alkyl)benzamides

Details Anti-emetic nortropyl(alkyl)benzamides Anti-emetic nortropyl(alkyl)benzamides

C - Chemistry, Metallurgy

07

D

260/270

C07D 451/04 (2006.01)

Patent

CA 1167443

ABSTRACT Compounds of the formula (I) and pharmaceutically acceptable salts thereof: Image (I) wherein: R1 is C1-6 alkyl; R2 is hydrogen or C1-7 acyl; R3 is C1-6 alkyl; R4 is a group CH2R5 wherein R5 is hydrogen, C3-8 cycloalkyl or phenyl optionally substituted by one or two substituents selected from C1-6 alkyl, C1-4 alkoxy, trifluoromethyl and halogen, having useful anti-emetic activity.

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