Process for the resolution of some interphenylene-9-...

Details Process for the resolution of some interphenylene-9-... Process for the resolution of some interphenylene-9-...

C - Chemistry, Metallurgy

07

D

260/310.1

C07D 277/14 (2006.01) C07D 417/12 (2006.01)

Patent

CA 1178283

16570 ABSTRACT OF THE DISCLOSURE Some derivatives of interphenylene-9-thia-11- oxo-12-azaprostanoic acid of the formula: Image which are active renal vasodilator agents are resolved via diastereomeric camphanyl or camphorcarbonyl esters. Upon hydrolysis, the separated diastereoisomers yield optically pure enantiomers.

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