Phenolic thioalkylamides as inhibitors of 5-lipoxygenase

C - Chemistry – Metallurgy – 07 – C

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167/268, 260/551

C07C 323/41 (2006.01) A61K 31/165 (2006.01)

Patent

CA 1330446

ABSTRACT The compounds of the present invention comprise substituted phenolic thioalkylamides that are specific inhibitors of 5-lipoxygenase and which, therefore, are useful in the treatment of local and systemic inflammation, allergy and hypersensitivity reactions and other disorders in which agents formed in the 5-lipoxygenase metabolic pathway are involved.

568604

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