Preparation of isothiazolones

Details Preparation of isothiazolones Preparation of isothiazolones

C - Chemistry, Metallurgy

07

D

260/310.3

C07D 275/02 (2006.01) C07D 275/03 (2006.01)

Patent

CA 1331190

PATENT APPLICATION OF George M. Lein, Jr. for PREPARATION OF ISOTHIAZOLONES DN86-64 TPS/sjv Abstract of the Disclosure Preparation of 3-isothiazolones by a single-kettle synthesis from a 3,3'-dithiodipropionic acid, a 3-thiopropionic acid, or their related acid halide by reacting sequentially with a thionyl halide (if the (di)acid halide has not previously been formed), followed by reaction with a halogenating agent, then a primary amine and base, and then with a halogenating agent. - i -

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