C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
167/41, 167/44,
C12N 5/00 (2006.01) A61K 39/395 (2006.01) A61M 1/36 (2006.01) C07K 16/18 (2006.01) G01N 33/543 (2006.01) G01N 33/86 (2006.01) A61K 38/00 (2006.01)
Patent
CA 1248472
ABSTRACT OF THE DISCLOSURE Hybridoma for production of monoclonal antibody to an antigen found on the peptide fragment of the B.beta. chain of human fibrinogen or fibrin I containing amino acid residues 1-42. The hybridoma is formed by fusing an animal myeloma cell, e.g., a mouse myeloma cell, with a splenocyte from an animal, e.g., a mouse, immunized with an NH2-terminal of human fibrinogen or fibrin.I. Hybridoma for production of monoclonal antibody to an antigen found on the peptide fragment of the B.beta. chain of human fibrin I1 containing amino acid residues 15-42. The hybridoma is formed by fusing an animal, e.g., mouse myeloma cell with a splenocyte from an animal, e.g., mouse, immunized with a NH2-terminal of human fibrin II. Diagnostic and therapeutic uses of the monoclonal antibodies are also disclosed.
467350
Kudryk Bohdan J.
Wiebe Michael E.
Macrae & Co.
New York Blood Center Inc.
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