Substituted pyrimidines

C - Chemistry – Metallurgy – 07 – D

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260/259, 167/7.1

C07D 239/50 (2006.01) A01N 43/54 (2006.01) A01N 57/32 (2006.01) C07D 239/48 (2006.01) C07D 403/04 (2006.01) C07F 9/6512 (2006.01)

Patent

CA 1292231

Substituted pyrimidines Abstract of the Disclosure The invention relates to novel substituted 2,4-diamino-5-cyano- pyrimidines of formula Image (I), wherein R1 is hydrogen, C1-C6alkyl, C2-C6alkenyl or C2-C6alkynyl, R2 is hydrogen, C1-C10alkyl or C3-C6cycloalky1, or R1 and R2,when taken together, are a radical selected from the group consisting of -(CH2)3-, -(CH2)4 and -(CH2)5, R3 is hydrogen or a radical -C0-R5 or -S02-R6, R4 is a radical selected from the group consisting of -NH2, -NH-C0-R5, -NH-S02-R6 , Image or -NH-CH=N-R10 ; R5 is hydrogen, C1-C12alkyl, C3-C6cycloalkyl, C1-C6alkoxy, per- halogenated C1-C3alkyl or the radical Image R6 is C1-C6alkyl, R7 is hydrogen or C1-C6alkyl,

535755

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Profile ID: LFCA-PAI-O-1252006

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