N-hydroxyethylated 2,4,6-triiodo-aminoisophthalic acid...

C - Chemistry – Metallurgy – 07 – D

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C07D 493/04 (2006.01) C07D 317/20 (2006.01) C07D 317/28 (2006.01) C07D 407/04 (2006.01)

Patent

CA 1189533

ABSTRACT Novel N-hydroxyethylated 2,4,6-triiodo-aminoiso- phthalic acid bis-trihydroxybutylamides of the general formula I Image (I) (in w hich each R represents trihydroxybutyl) and a process for their manufacture. The novel compounds being radio-opaque are out- standingly suitable for use as X-ray contrast agents having an excellent tolerability and good water-solu- bility and may be used for various examination methods using X-ray diagnosis; they may accordingly be made up into X-ray contrast preparations with physiologically tolerable carriers.

418020

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