Coating medical devices with cationic antibiotics

Details Coating medical devices with cationic antibiotics Coating medical devices with cationic antibiotics

A - Human Necessities

61

L

167/328

A61L 27/00 (2006.01) A61L 27/54 (2006.01) A61L 29/16 (2006.01) A61L 33/00 (2006.01) H01J 29/07 (2006.01)

Patent

CA 1308360

Abstract of the Disclosure A medical device having long-lasting bactericidal properties and a method for making the same is provided. The material from which the medical device is made, the substrate, carries a negatively-charged group having a pKa of less than 6. A cationic antibiotic is ionically bonded to the negatively-charged group. The negatively-charged group may be a portion of a larger carrier molecule. The carrier molecule is bound to the substrate such that the negatively-charged group is exposed for ionic interaction with the cationic antibiotic. Heparin is an ideal carrier molecule because it has both anti-bacterial adhesion activity and anti-thrombogenic activity.

584987

Affiliated with

Also associated with

Rating

Coating medical devices with cationic antibiotics does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Coating medical devices with cationic antibiotics, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Coating medical devices with cationic antibiotics will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1252538