6-(1h-tetrazol-5-yl)thieno[3,2-6]pyridin-5(4h)-one compounds

Details 6-(1h-tetrazol-5-yl)thieno[3,2-6]pyridin-5(4h)-one compounds 6-(1h-tetrazol-5-yl)thieno[3,2-6]pyridin-5(4h)-one compounds

C - Chemistry, Metallurgy

07

D

167/231, 260/276

C07D 495/04 (2006.01) A61K 31/44 (2006.01)

Patent

CA 1293257

ABSTRACT (1H-Tetrazol-5-yl)thienopyridinones and related compounds which have the formula Image wherein Th is a thiophene fused to the pyridine ring and n is 0, 1 or 2; or a pharmaceutically acceptable salt thereof, and which are useful as antiallergic agents are described herein. The compounds are pre- pared by the reaction of an appropriate cyanoketone of the formula Image wherein Th and n are defined as above, with ammonium chloride and an azide in an inert solvent. Sodium azide is a preferred azide although other alkali metal azides could be used. A preferred solvent is dimethylformamide.

492239

Affiliated with

Also associated with

Rating

6-(1h-tetrazol-5-yl)thieno[3,2-6]pyridin-5(4h)-one compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 6-(1h-tetrazol-5-yl)thieno[3,2-6]pyridin-5(4h)-one compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 6-(1h-tetrazol-5-yl)thieno[3,2-6]pyridin-5(4h)-one compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1254382