Determination of protecting anti-hbv immunoglobulins

Details Determination of protecting anti-hbv immunoglobulins Determination of protecting anti-hbv immunoglobulins

G - Physics

01

N

167/37

G01N 33/576 (2006.01)

Patent

CA 1233116

23894-193 ABSTRACT A novel test kit for detecting or determining immuno- globulins which protect against hepatitis B infection comprises: (a) a given quantity of insolubilized hepatitis B surface antigens of the antigenic type AX, wherein A represents one or more epitopes common to all hepatitis B surface antigen types, and X represents a combination of the epitopes which are not common to all hepatitis s surface antigen types; and (b) a given quantity of labelled hepatitis B surface antigens of the anti- genic type AZ, wherein A is as defined above and Z represents a combination of the epitopes which are not common to all hepatitis B surface antigen types, and wherein X and Z do not contain any epitopes in common. Immunoglobulin reagents comprising parts (a) and (b) of the test kit also comprise part of the invention along with a method for detecting or determining immunoglobulins which protect against hepatitis B.

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