Process for resotropin

Details Process for resotropin Process for resotropin

C - Chemistry, Metallurgy

07

D

260/248.1

C07D 487/22 (2006.01) C07D 487/18 (2006.01)

Patent

CA 1275408

ABSTRACT A method is provided for preparing resotropin by reacting hexamethylenetetramine and resorcinol in a solvent consisting essentially of methanol in an amount sufficient to dissolve substantially all of said reactants. The resulting product has greatly improved storage stability, is formed in greater yield and with higher purity, by comparison with previous methods of preparation using solvents other than methanol, such as water and various non-aqueous solvents.

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