A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/159, 167/246
A61K 31/04 (2006.01) A61K 9/00 (2006.01) A61K 9/14 (2006.01) A61K 9/70 (2006.01) A61K 31/21 (2006.01)
Patent
CA 1218604
- 1 - Abstract A trinitroglycerol containing substantially disaccharide-free polymeric diffusion matrix is provided for the transdermal systemic delivery of trinitroglycerol through the skin of a patient. The polymeric diffusion matrix contains sufficient trinitroglycerol to be re- leased over a prolonged period of time and comprises 10 to 40 percent by weight of a first lower molecular weight, partial hydrolyzed polyvinylalcohol component with a mole- cular weight of from 5,000 to 40,000 and with a degree of hydrolysis of 75 to 92 percent and 2 to 15 percent by weight of a second higher molecular weight, essentially fully hydrolyzed polyvinylalcohol component with a mole- cular weight of from 90,000 to 150,000 and with a degree of hydrolysis of at least 95 percent and 2 to 25 percent by weight of glycerol.
406809
Key Pharmaceuticals Inc.
Kirby Eades Gale Baker
LandOfFree
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