Bis-hydroxymethyl carbonate bridged antibacterial agents

Details Bis-hydroxymethyl carbonate bridged antibacterial agents Bis-hydroxymethyl carbonate bridged antibacterial agents

C - Chemistry, Metallurgy

07

D

260/114.1, 260/1

C07D 499/32 (2006.01)

Patent

CA 1214161

BIS-HYDROXYMETHYL CARBONATE BRIDGED ANTIBACTERIAL AGENTS Abstract Antibacterial agents in which a penicillin and a beta-lactamase inhibitor are linked by means of a bis-hydroxymethyl carbonate bridge are of the formula Image ---(I) and pharmaceutically acceptable acid addition salts thereof, wherein R1 is hydrogen, hydroxy, certain acyloxy or certain alkoxycarbonyloxy groups, a process for their preparation, and intermediates useful in their production.

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