Antihypertensive derivatives of 1,4-dihydropyridine

Details Antihypertensive derivatives of 1,4-dihydropyridine Antihypertensive derivatives of 1,4-dihydropyridine

C - Chemistry, Metallurgy

07

D

260/246.2, 260/2

C07D 413/00 (2006.01) C07D 211/30 (2006.01)

Patent

CA 1175825

ABSTRACT OF THE DISCLOSURE Antihypertensive compounds of the formula Image wherein R5 is H, alkyl, aryl, halo, lower alkoxy, nitro amino, alkylmercapto, cyano, carboxy, carbalkoxy, sulfamyl, trifluoromethyl, hydroxy, acyloxy, methane- sulfonyl, alkylamino or acylamino; and each R1 and R2 is alkyl; wherein the alkyl, alkoxy and aryl groups contain up to 10 carbon atoms and non-toxic, pharmaceutically- acceptable acid addition salts thereof.

370606

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