Pharmaceuticals microencapsulated by vapor deposited...

A - Human Necessities – 61 – K

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A61K 9/50 (2006.01) A61K 9/58 (2006.01) B01J 13/02 (2006.01)

Patent

CA 1337398

A microencapsulated pharmaceutical is formed by vapor depositing a polymeric film about an active pharmaceutical agent. The film thickness of the vapor deposited film is controlled to provide effective controlled release of said pharmaceutical agent subsequent to application. In a preferred embodiment the pharmaceutical is an orally ingestible pharma- ceutical formed by vapor deposition of a poly-p- xylylene polymer about a core comprising an active pharmaceutical agent. The pharmaceutical agent exhibits surprising controlled release activity inspite of the extreme inertness of vapor deposited films such as Parylene films.

610931

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