Process for preparing mycarosyltylactone

C - Chemistry – Metallurgy – 12 – P

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C12P 19/62 (2006.01) A61K 31/365 (2006.01) A61K 31/70 (2006.01) C12N 1/20 (2006.01) C12P 17/08 (2006.01) C12P 19/00 (2006.01)

Patent

CA 1172191

X-5659 Abstract of the Invention A new microorganism, Streptomyces fradiae NRRL 12201, which produces mycarosyltylactone (5- O-mycarosyl-20-dihydro-20,23-dideoxytylonolide) and 2 process for preparing tylactone (20-dihydro-20,23- dideoxytylonolide) and mycarosyltylactone by submerged aerobic fermentation of this microorganism, or a mycarosyltylactone-producing mutant or recombinant thereof, are provided.

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