Processes for preparing piroxican and intermediates leading...

C - Chemistry – Metallurgy – 07 – D

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260/309.1

C07D 275/06 (2006.01)

Patent

CA 1190232

PROCESSES FOR PREPARING PIROXICAM AND INTERMEDIATES LEADING THERETO Abstract Intermediates for the preparation of the antiinflamma- tory agent piroxicam and their process of preparation which com- prises reacting N-methylsaccharin with alkyl haloacetates in the presence of an appropriate base to give the intermediates alkyl 2-(2-methyl-3-hydroxy-2,3-dihydro-1,2-benzisosulfonazol-3-yl)-2- haloacetate which can then be converted into piroxicam.

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