Production of human serum albumin by fermentation

C - Chemistry – Metallurgy – 12 – N

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C12N 15/14 (2006.01) C07K 14/765 (2006.01) C12N 1/16 (2006.01) C12N 1/38 (2006.01) C12N 15/67 (2006.01) C12P 21/02 (2006.01)

Patent

CA 1336416

The yield of secreted human serum albumin in a fermentation of genetically engineered yeast can be increased if a polyoxyalkylene compound is added, for example, polypropylene glycol or polyoxypropylene/polyoxyethlene copolymers. Some of these compounds are routinely used in fermentation as antifoam compounds, but at lower levels.

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