C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/299
C07D 487/04 (2006.01) A61K 31/40 (2006.01)
Patent
CA 1177832
Isomerization of .beta.-Lactam Compounds and Novel Products Obtained Thereby Abstract of the disclosure Compounds of the formula (I): Image (I) wherein R is an ethyl group which may optionally be sub- stituted and n is 0 or 1, or a physiologically acceptable salt thereof, can be produced by subjecting to isomerization a compound of the formula (II): Image (II) wherein R and n have the same meaning as defined above, or a salt thereof, by using a quaternary ammonium halide and are useful as a bactericide or disinfectant, and also a synergistic effect with penicillin and/or cephalosporin antibiotic agents. Among the compounds of the formula (I), compounds shown by the formula: Image wherein R6 is H or -SO3H, as well as salts thereof, are novel.
397177
Asai Mitsuko
Harada Setsuo
Tsubotani Shigetoshi
Fetherstonhaugh & Co.
Takeda Chemical Industries Ltd.
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