Thiophene sulfonamide antiglaucoma agents

Details Thiophene sulfonamide antiglaucoma agents Thiophene sulfonamide antiglaucoma agents

C - Chemistry, Metallurgy

07

D

167/207, 260/328

C07D 333/34 (2006.01) A61K 31/38 (2006.01) C07D 409/12 (2006.01)

Patent

CA 1328261

TITLE OF THE INVENTION THIOPHENE SULFONAMIDE ANTIGLAUCOMA AGENTS ABSTRACT OF THE DISCLOSURE Aryl (or aralkyl)-sulfonylthiophene-2- sulfonamides containing a basic functional group as a substituent are efficacious in the treatment of elevated intraocular pressure and glaucoma following topical ocular administration. The compounds of the invention have the structural formula: Image

568886

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