Penetration enhancers for transdermal delivery of systemic...

Details Penetration enhancers for transdermal delivery of systemic... Penetration enhancers for transdermal delivery of systemic...

A - Human Necessities

61

K

167/159, 167/208

A61K 47/22 (2006.01)

Patent

CA 1319613

ABSTRACT OF THE DISCLOSURE This invention relates to a method for administering systemically active agents including therapeutic agents through the skin or mucosal membranes of humans and animals in a transdermal device or formulation comprising topically administering with said systemic agent an effective amount of a membrane penetration enhancer having the structural formula Image wherein X may represent sulfur or two hydrogen atoms; R' is H or a lower alkyl group having 1-4 carbon atoms; m is 2-6; n 15 0-18 and R is -CH3, Image or Image wherein R" is H or halogen.

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