Substituted pyridazinones, processes for producing them,...

C - Chemistry – Metallurgy – 07 – D

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C07D 413/10 (2006.01) A61K 31/535 (2006.01) C07D 237/04 (2006.01)

Patent

CA 1244419

Substituted pyridazinones, processes for producing them, pharmaceutical preparations containing these compounds, and the use thereof Abstract The present invention relates to novel substituted pyridazinones of the general formula I Image (I) wherein R is a halogen atom, a lower alkyl or lower alkoxy group, the nitro, hydroxyl, cyano, carboxyl, lower alkoxy- carbonyl or carbamoyl group or the trifluoromethyl group, and Z is hydrogen or an acyl group, and the salts and tautomeric forms thereof, which have a marked anti- thrombotic action, to the production of these novel compounds, to pharmaceutical preparations containing them, and to their use.

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