Preparation of an antibiotic selectively effective against...

C - Chemistry – Metallurgy – 12 – N

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195/89, 195/34.8

C12N 1/20 (2006.01) C07K 14/195 (2006.01) C12P 1/06 (2006.01) C12P 21/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1211392

Preparation of an Antibiotic Selectively Effective Against Staphylococcus Infections ABSTRACT A strain (ATCC 31918) of Rothia dentocariosa which, upon fermentation, produces an antibiotic - staphylocidin which is selectively effective against staphylococci, particularly those associated with S. aureus and S. epidermidis; and a process for producing such antibiotic by cultivation of the strain under aerobic conditions. Staphylocidin-containing products comprising the cell mur- ein from the fermentation product are also disclosed.

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