Method of treating tumor cells by inhibiting growth factor...

Details Method of treating tumor cells by inhibiting growth factor... Method of treating tumor cells by inhibiting growth factor...

C - Chemistry, Metallurgy

12

N

167/129, 167/139

C12N 5/10 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) C07K 16/22 (2006.01) C07K 16/30 (2006.01) C07K 16/32 (2006.01) C12N 15/02 (2006.01) C12P 21/08 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1341082

A method of inhibiting growth of tumor cells which overexpress a growth factor receptor or growth factor by treatment of the cells with antibodies which inhibit the growth factor receptor function, is disclosed. A method of treating tumor cells with antibodies which inhibit growth factor receptor function, and with cytotoxic factor(s) such as tumor necrosis factor, is also disclosed. By inhibiting growth factor receptor functions tumor cells are rendered more susceptible to cytotoxic factors.

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