C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
167/130, 167/322
C12N 7/00 (2006.01) A61K 39/12 (2006.01) A61K 39/165 (2006.01) A61K 39/20 (2006.01) A61K 39/295 (2006.01)
Patent
CA 1331339
ABSTRACT The invention relates to process for stabilizing attenuated virus, notably measles, rubella, mumps vaccines and associated vaccines which are kept in lyophilized form in the presence of at least one lyophilization excipient, characterized in that a suitable amount of at least one compound of the general formula Image wherein R1 is an oxygen atom or a sulphur atom and R2 is a NH2 group or a linear chain, unsaturated or not, of type: -O-C..., -NH-C..., or -C..., possibly hydroxyl-substituted, is added, preferably before lyophilization.
603871
Francon Alain Jean-Louis
Montagnon Bernard Jean
Fetherstonhaugh & Co.
Pasteur Merieux Serums Et Vaccins
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