Synthesis of phenylacetic acid esters

C - Chemistry – Metallurgy – 07 – C

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260/477.5

C07C 69/612 (2006.01) C07C 45/67 (2006.01) C07C 69/736 (2006.01)

Patent

CA 1197522

ABSTRACT OF THE DISCLOSURE Esters of phenylacetic acids are prepared in a single step by hydrolysis of 2,2,2-trichloro- 1-phenylethanes in inorganic basic media. These esters, which are useful as intermediates in the preparation of herbicides, have the formula Image wherein: R is C1-C6 primary or secondary alkyl or C3-C6 cycloalkyl; the R1 groups are independently chloro, fluoro, bromo, iodo, C1-C3 alkyl, C1-C3 alkoxy, nitro, or trifluoromethyl; n is 0-3, provided that n is 3 only when the R1 groups are chloro or bromo.

430105

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