Chimeric antibody with specificity to human b cell surface...

Details Chimeric antibody with specificity to human b cell surface... Chimeric antibody with specificity to human b cell surface...

C - Chemistry, Metallurgy

07

K

167/101, 167/129

C07K 16/46 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 51/10 (2006.01) C07K 16/28 (2006.01) C07K 19/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1336826

A chimeric antibody with human constant region and murine variable region, having specificity to a 35 kDA polypeptide (Bp35(CD20)) expressed on the surface of human B cells, methods of production, and uses. The chimeric antibody of the invention can be utilized for passive immunization without negative immune reactions, and also in immunodiagnostic assays and kits.

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