Method for enhancing production of secondary metabolites...

C - Chemistry – Metallurgy – 12 – N

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195/1.22, 195/1.

C12N 1/15 (2006.01) C07H 21/04 (2006.01) C12N 15/52 (2006.01) C12N 15/80 (2006.01) C12P 37/00 (2006.01)

Patent

CA 1340916

Clustered antibiotic biosynthetic genes are employed for improvement of production of the antibiotic in microorganisms and for the isolation of other genes involved in the biosynthesis of the antibiotic. The invention is exemplified with improved production of penicillin in Penicillium chrysogenum, with the isolation of another clustered biosynthetic gene(s) and with the expression of penicillin biosynthetic genes in Acremonium chrysogenum.

608022

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