Imidazolyl, triazolyl, and tetrazolyl compounds

Details Imidazolyl, triazolyl, and tetrazolyl compounds Imidazolyl, triazolyl, and tetrazolyl compounds

C - Chemistry, Metallurgy

07

D

167/233, 260/305

C07D 233/56 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01) C07D 521/00 (2006.01)

Patent

CA 1256112

Abstract A series of imidazolyl, triazolyl and tetrazolyl compounds of the formula Image wherein Q is hydrogen or methyl, A is a bond, -CH2-, -O-, or -S-; E and D are independently CH or N; and R1 and R2 are each independently hydrogen, C1-C3 alkyl, halo, trifluoromethyl, or C1-C3 alkoxy, or a pharmaceutically acceptable salt thereof, are useful pharmaceuticals which inhibit aromatase in the body and are accordingly used to treat and prevent estrogen- dependent diseases.

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