Synthetic picornavirus antigen

Details Synthetic picornavirus antigen Synthetic picornavirus antigen

C - Chemistry, Metallurgy

07

K

167/130, 167/139

C07K 7/08 (2006.01) A61K 39/125 (2006.01) C07K 14/085 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1253298

Abstract of the Disclosure A specific synthetic antigenic peptide that contains a sequence of about 20 amino acid residues corresponding to a certain region of the antigenic Picornavirus capsid protein such as the VPl capsids of foot-and-mouth disease and poliomyelitis viruses. That region is located at a distance of about 60 to about 75 percent of the total amino acid length measured from the amino-terminus. Specific synthetic peptide-containing vaccines that produce antibodies that protect animal hosts from the Picornaviruses, as well as antibodies to and diagnostics for Picornavirus antigens are disclosed.

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