Receptor-based histamine assay

C - Chemistry – Metallurgy – 12 – Q

Patent

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150/14, 167/37

C12Q 1/42 (2006.01) G01N 33/53 (2006.01) G01N 33/94 (2006.01)

Patent

CA 1212045

-1- Abstract of the Disclosure A receptor-based clinical or research competitive inhibition assay method for determining histamine in body or laboratory fluids is disclosed A kit for carrying out the method is also described comprising an amount of histamine receptors sufficient to provide an excess of receptors for binding with the amount of histamine in the sample to be assayed, and an amount of a histamine- indicator conjugate sufficient to react with the resulting unbound histamine receptors present after reaction of the histamine sample with the histamine receptors.

440867

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