Pyridine derivatives, process for their preparation and...

C - Chemistry – Metallurgy – 07 – D

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260/297.95

C07D 213/30 (2006.01)

Patent

CA 1210010

Abstract The invention relates to new pyridine derivatives of the formula (I) Image wherein R1 and R2 independently represent hydrogen, halogen, trihalomethyl, alkyl having from one to 4 carbon atoms or alkoxy having from one to 4 carbon atoms, and acid addition and quaternary ammonium salts thereof. According to another aspect of the inven- tion there are provided processes for the preparation of these compounds. The compounds of the formula (I) are pharmacologically active. In particular, they inhibit the microsomal monooxigenase enzyme system of the liver. Pharmaceutical compositions containing them as active ingredient are also within the scope of the invention.

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