Ph independent controlled release tablets

Details Ph independent controlled release tablets Ph independent controlled release tablets

A - Human Necessities

61

K

167/219

A61K 31/505 (2006.01) A61K 9/20 (2006.01) A61K 9/22 (2006.01)

Patent

CA 1219216

ABSTRACT Novel pH independent, controlled release, orally administrable tablets comprising an effective amount of an intimate mixture of dipyridamole or an acid addition salt thereof, at least 18 acid equivalents of at least one pharmaceutically acceptable solid acid or acidic substance per mole of dipyridamole and a disintegration agent in an amount sufficient to allow at least 90% dissolution of the dipyridamole or the salt thereof in the gastrointestinal pH range 1 to 7 over a period of 1 hour or less.

451489

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