Dentifrice containing dual sources of fluoride

Details Dentifrice containing dual sources of fluoride Dentifrice containing dual sources of fluoride

A - Human Necessities

61

K

167/318.1

A61K 8/21 (2006.01) A61K 8/25 (2006.01) A61Q 11/00 (2006.01)

Patent

CA 1247531

ABSTRACT OF THE DISCLOSURE Dentifrice comprising a liquid vehicle containing water, a gelling agent, a dual source of at least about 500 ppm of fluorine comprising sodium fluoride and sodium monofluorophosphate, a precipitated, amorphous silica gel having an average particle size of 1 to 30 microns and a) a surface area of 1 to 600 m2/g, b) a pore volume of 0.05 to 0.5 cm3/g, c) a product of surface area (in m2/g) x pore volume in cm3/g) less than or equal to 240, d) a calculated pore diameter of 1.5 to 2.5 nm, and e) a water content of less than 25% by weight, a source of calcium corresponding to up to about 0.004% by weight (40 ppm) of calcium ion and about 0.25%-5% by weight of an alkali metal phytate. The alkali metal phytate improves retention of total soluble fluorine, the dentifrice being stable in an unlined aluminium tube.

473231

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