A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/255, 167/263
A61K 31/22 (2006.01) A61K 31/19 (2006.01) A61K 31/23 (2006.01)
Patent
CA 1292695
ANAEROBE-SELECTIVE ANTIBACTERIAL COMPOSITIONS AND METHODS ABSTRACT OF THE DISCLOSURE This invention relates to pharmaceutical compositions com- prising anaerobe-selective antibacterial agents which are substi- tuted or unsubstituted 1 ,12-dodecanedioic peroxy acids, or their pharmaceutically-acceptable salts or esters. The pharmaceutical compositions of the present invention are especially suitable for oral administration in the form of mouth rinses and toothpastes. These anaerobe-selective antibacterial compositions are useful for treating or preventing anaerobic bacterial infections, especially diseases of the oral cavity, in humans or lower animals. The present invention further relates to a method for treat- ing or preventing anaerobic bacterial infections such as acne, and especially - diseases of the oral cavity such as gingivitis and periodontal disease, in humans or lower animals. The method comprises topically contacting the anaerobe-containing tissue of the human or lower animal with a safe and effective amount of an anaerobe-selective antibacterial agent selected from substituted or unsubstituted 1,12-dodecanedioic peroxy acids, or their pharma- ceutically-acceptable salts or esters.
525611
Kirby Eades Gale Baker
Sampathkumar Padmini
The Procter & Gamble Company
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