Nalbuphine-local anesthetic analgesic composition and method...

Details Nalbuphine-local anesthetic analgesic composition and method... Nalbuphine-local anesthetic analgesic composition and method...

A - Human Necessities

61

K

167/227

A61K 31/445 (2006.01) A61K 31/165 (2006.01) A61K 31/245 (2006.01)

Patent

CA 1280695

TITLE NALBUPHINE-LOCAL ANESTHETIC ANALGESIC COMPOSITION AND METHOD OF PRODUCING ANALGESIA Abstract of the Disclosure An analgesic composition, particularly in an injectable or opthalmic dosage form, is provided which provides a fast onset of action and an extended dura- tion of action with smaller amounts of the active ingredients. The composition contains nalbuphine or pharmaceutically suitable salt thereof and at least one local anesthetic such as bupivacaine, mepivacaine, and tetracaine. A method of producing analgesia in a mammal is also provided by administering to a mammal intra- venously, intraocularly or epidurally nalbuphine or a pharmaceutically suitable salt thereof and at least one local anesthetic.

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