Sac including a detectable marker and use thereof in an assay

Details Sac including a detectable marker and use thereof in an assay Sac including a detectable marker and use thereof in an assay

G - Physics

01

N

150/14, 150/3

G01N 33/548 (2006.01) A61K 9/127 (2006.01) G01N 33/532 (2006.01) G01N 33/76 (2006.01)

Patent

CA 1274158

ABSTRACT OF THE DISCLOSURE A sac, in particular a vesicle, including as a detect- able marker an absorbing dye having an extinction coefficient of at least 100,000 and a solubility in water of at least 0.1M; in particular, sulforhodamine B or salt thereof. The sacs have improved stability to leakage and are useful in a variety of assays; in particular, when sensitized with a ligand.

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