Substituted aminoalkanoylaminoalkyl phosphonate angiotensin...

C - Chemistry – Metallurgy – 07 – F

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C07F 9/572 (2006.01) A61K 31/675 (2006.01) C07F 9/40 (2006.01) C07F 9/576 (2006.01) C07F 9/6506 (2006.01) C07F 9/6561 (2006.01)

Patent

CA 1307787

HA378a ABSTRACT SUBSTITUTED AMINOALKANOYLAMINOALKYL PHOSPHONATE ANGIOTENSIN CONVERTING ENZYME INHIBITORS Compounds of the formula Image wherein X is various amino or imino acids and esters are disclosed. These compounds are useful as anti-hypertensive agents due to their angiotensin converting enzyme inhibition activity and depending upon the definition of X may also be useful as analgesics due to their enkephalinase inhibition activity.

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